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To reduce the related bias, all patients were interviewed in the 3 rd and 6 th weeks after the treatment by a psychiatrist who did not know the status of the patients in the two study groups

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ATP-binding cassette (ABC) transporters and drug efflux One of the most well-documented mechanisms of drug resistance in CSCs is their elevated expression of ABC transporters, which actively pump chemotherapeutic agents out of the cell, reducing intracellular drug accumulation and efficacy