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Intracellular Signaling Pathways Experimental studies have examined Melanotan II in relation to intracellular signaling pathways commonly associated with melanocortin receptor activity, including cyclic AMP (cAMP)-related signaling processes

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In 20–50% of cases, this syndrome is induced by a deletion in the NIPBL gene on chromosome 5 (locus 5p13) [386, 387]