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However, in contrast to simple obesity, where GH is low and IGF-I within normal range (89), subjects with MASLD demonstrate variable changes in the GH/IGF-I axis depending on disease severity (121–123) ( Table 1 )

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DHA represents the most significant omega-3 PUFA in the brain, comprising over 40% of the brain’s total omega-3 content, especially concentrated within the gray matter (13)